Tumor Profiling

CancerGuide, utilizing the CancerGuide Tumor Knowledge Database, rigorously-validated scientific methods, and the global Esoterix Clinical Trials Services division of LabCorp, has the following expert molecular profiling and service capabilities:

 profiling of predicted response rate of candidate drugs across annotated tumor collections in target indications

customized comparative assessments of current therapies on the market utilizing the robust bank of response profiles on tumor collections

 assessment of the degree of overlap of response profile of molecules or candidate drug(s) to existing treatments, allowing for the selection of targeted therapeutics that fulfill unmet need

CancerGuide’s panel of current companion diagnostic tests and custom-developed tests can be utilized in several different ways to: 

  identify and enrich target populations for your candidate drugs, enabling them to gain rapid clinical adoption in market segments.

 reposition drugs currently approved for second line treatment as a first line option by demonstrating efficacy in a population resistant to standard care. 

select indications with the appropriate profile of tumor types to maximize commercial success.

 derive new combinations of drugs for further development and potentially ‘rescue’ pipeline drugs that have faltered because of poor response profiles. 

These projects will allow for real-time use of genomic data to determine treatment or eligibility, unlike post hoc correlative studies, allowing for smaller, more precise trials, giving the drug developer actionable information to complete clinical development faster with less investment.

CancerGuide, in conjunction with Esoterix Clinical Trial Services, performs these services generally on a fee for service basis. CancerGuide also has a flexible and client-conducive approach to intellectual property related to any resulting intellectual property.

If you are a drug developer, interested in these valuable services, please register by emailing us at pharmaservices@cancerguidedx.com.  Please include a brief description of the nature of your project and inquiry.  We look forward to hearing from you.